November 6, 2013
Cannabis and the unique chemical compounds produced by the plant, called cannabinoids, have been at the center of one of the most exciting—and underreported—developments in modern science. Research on marijuana’s effects led directly to the discovery of a molecular signaling system in the human brain and body, the endocannabinoid system, which plays a crucial role in regulating a broad range of physiological processes: hunger, sleep, inflammation, stress, blood pressure, body temperature, glucose metabolism, bone density, intestinal fortitude, reproductive fertility, circadian rhythms, mood and much more.
Within the scientific community, the discovery of the endocannabinoid system is increasingly recognized as a seminal advance in our understanding of human biology. The Rubicon was crossed in 1988, when a government-funded study at the St. Louis University School of Medicine determined that the mammalian brain has an abundance of receptor sites—specialized protein molecules embedded in cell membranes—that respond pharmacologically to compounds in cannabis.