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In one of the first studies to show a significant association between BPA and cancer development, University of Michigan School of Public Health researchers have found liver tumors in mice exposed to the chemical via their mothers during gestation and nursing.
"We found that 27 percent of the mice exposed to one of three different doses of BPA through their mother's diet developed liver tumors and some precancerous lesions. The higher the dosage, the more likely they were to present with tumors," said Caren Weinhouse, U-M doctoral student in the School of Public Health's Department of Environmental Health Sciences and first author of the paper published online Feb. 3 in Environmental Health Perspectives.
Mice whose mothers received the highest dosage, 50 mg of BPA per kg diet, were seven times more likely to have tumors than those whose mothers were not exposed to BPA.